Review: NIOD’S Multi-Molecular Hyaluronic Complex

The formula offers a multi-dimensional approach to topical hyaluronic supplementation by combining 15 forms of hyaluronic compounds, hyaluronic precursors and a hyaluronic support technology in a peptide-charged delivery system. It offers water-based hydration and helps skin surface look plump, elastic, comfortable and uniform. 


I was really looking forward to this product, but the old saying “big things come in small packages” rang tragically true here – NIOD’s Multi-Molecular Hyaluronic Complex came in an deceptively small bottle (with an even smaller amount of product) for $35 and it made my skin react like nothing before. I’ve only been able to try this out for perhaps a week and half, but given how terribly my skin is reacting, I’ll be ceasing use (applying the remaining half of the bottle onto my elbows and knees, for which it has had no visible effect). For those interesting in trying this product out, the application was, at least, quite easy – carrying a thin, water-like texture and absorbing into my skin with great haste.

Ingredient Pros and Cons

Ingredients:Aqua (Water), Hydrolyzed Yeast Extract, Glycerin, Hyaluronic Acid, Sodium Hyaluronate, Sodium Butyroyl Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Disodium Acetyl Glucosamine Phosphate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Pseudoalteromonas Exopolysaccharides, Tamarindus Indica Seed Gum, Tremella Fuciformis Sporocarp Extract, Ceratonia Siliqua Gum, Myristoyl Nonapeptide-3, Plantago Lanceolata Leaf Extract, Salvia Sclarea Extract, Arginine, Aspartic Acid, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, PCA, Sodium PCA, Betaine, Sodium Lactate, Epigallocatechin Gallatyl Glucoside, Gallyl Glucoside, Algae Extract, Sodium Salicylate, Lecithin, Polyglucuronic Acid, Xanthan Gum, Trisodium Ethylenediamine Disuccinate, Sclerotium Gum, Pullulan, Cetyl Hydroxyethylcellulose, Propanediol, Pentylene Glycol, Dimethyl Isosorbide, Citric Acid, Magnesium Chloride, Silica, Polysorbate 20, Ethoxydiglycol, Propyl Gallate, Dehydroacetic Acid, Benzyl Alcohol, Potassium Sorbate, Sodium Benzoate, Ethylhexylglycerin, 1,2-Hexanediol, Caprylyl Glycol, Phenoxyethanol.

Significant Pros

  • Hydrolyzed Yeast Extract (moisturizing)
  • Glycerin (hydrating, moisturizing)
  • Hyaluronic Acid, Sodium Hyaluronate, Sodium Butyroyl Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate (hydrating, soothing)
  • Tremella Fuciformis Sporocarp Extract (antioxidant, moisturizing)
  • Myristoyl Nonapeptide-3 (moisturizing, healing)
  • Betaine (moisturizing, soothing)
  • Algae Extract (moisturizing)
  • Polyglucuronic Acid (moisturizing)
  • . . . And so much more!

Significant Cons

  • Dehydroacetic Acid (drying)

The Takeaway

There are so many incredible ingredients in this product, so it’s quite unfortunate that this it didn’t work out for me. Perhaps it contained an overload of chemicals my skin couldn’t handle, for even when used in isolation, the serum seemed to irritate my skin. Normally, I would still encourage other people to give this a shot, since everyone’s skin is different, but the price is so exorbitant compared to what you get, I can’t in good faith say this is a good investment. Even if this product works, you’ll have to purchase a multitude over the course of a few months until you see a real result.

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